In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

Magnesium can be made by several methods (Fig. 1), but the most common method of manufacture is by the electrolytic process, as for example the electrolysis of magnesium chloride.

By September, demand in the construction sector had significantly increased; however, resurgent cases of virus hindered the anticipated recovery in demand. However, due to a severe fall in market fundamentals in some end-use areas, its prices had significantly faded by quarter-end. Delays in a number of commercial projects, followed by a poor recovery in the downstream automotive market, were identified as primary causes of the protracted recovery curve.