According to the feedback of manufacturers, the recent mainstream factory new single price, the market as a whole into the center of gravity. On the demand side, the terminal in August is still the off-season, many downstream still have inventory use, the current batch purchase intention is limited, and the market turnover is low. Some plastics and papermaking related downstream feedback part of the signal price is high. Recent titanium dioxide raw material price shock is strong, titanium dioxide price upward support has been enhanced, comprehensive market factors, the current titanium dioxide market into the stable price state after rising.
- As a critical component in these diverse applications, the supply chain of micro TiO2 is vital
micro titanium dioxide supplier. Several leading suppliers globally ensure a consistent and high-quality source of this material. Companies like Evonik, Cristal Global, Tronox, and Venator Materials are renowned for their expertise in titanium dioxide production. These companies utilize advanced manufacturing techniques to produce micro TiO2 with tailored properties to meet specific customer requirements.
JECFA also evaluated estimates of dietary exposure to titanium dioxide, estimating the maximum 95th percentile of exposure to be 10 mg/kg BW per day. Overall, considering the low oral absorption of titanium dioxide as a food additive, the committee reaffirmed the ADI “not specified” that was established at the 13th meeting.


Why does the exposure route matter, and what's the risk?
Overwhelmingly, research that’s relevant to human eating patterns shows us that E171 is safe when ingested normally through foods and drugs (1,2).


How can food businesses comply with this Regulation?
Nano titanium dioxide is a versatile material that is used in many different industries due to its unique properties. As a leading manufacturer of nano titanium dioxide, we pride ourselves on producing high-quality products that meet the needs of our customers.
The reaction liquid is filtered through plate and frame pressure to obtain lithopone in the form of a filter cake with a moisture content of no more than 45%. It is then roasted in a drying furnace to change the crystal form of lithopone, and is then pickled with sulfuric acid at a temperature of 80°C. Finally, it is washed with water, reinforced with colorants, filtered, dried and ground into powder.
A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”
For that reason, the Center for Science in the Public Interest has graded titanium dioxide as a food additive that consumers should seek to “avoid.” Scientists at the nonprofit nutrition and food safety watchdog group today published a new entry for titanium dioxide in its Chemical Cuisine database of food additives.
ROS were detected through the colorimetric assay employing the nitro-blue tetrazolium salt (NBT salt) by reading the absorbance of the reduced blue molecule.

Made Safe only allows titanium dioxide as part of sunscreen solutions and diaper creams; all titanium dioxide must be non-nanoparticle. Made Safe does not allow titanium dioxide in any other personal care or household products.
lithopone supplier 30% complies with both the REACH and Indirect Food Regulations, as well as with many European regulations regarding Toys, Packaging, Resins, etc…

The availability of other white pigments poses a major challenge for the Lithopone market during the forecast period. Other alternatives to Lithopone include Zinc White, Titanium Dioxide, Calcium Carbonate, Blanc Fixe, and Barytes. The use of TiO2 has reduced the commercial significance of the Lithopone in the pigments industry.
Where does titanium dioxide come from?
No acute effects of nano-sized TiO2 were observed in Danio rerio (zebrafish) embryos. Exposure of rainbow trout to TiO2 NPs triggered lipid peroxidation, influence on the respiratory tract, disturbance in the metabolism of Cu and Zn, induction of intestinal erosion and accumulation in kidney tissue. Linhua et al. exposed juvenile carp to 100 and 200 mg/ml of particles and TiO2 observed no mortality. However, the fish suffered from oxidative stress and pathological changes in gill and liver. In the infaunal species Arenicola marina, exposure to TiO2 NPs in sediment caused sub-lethal effects including decrease in casting rate and increase in cellular and DNA damage. Aggregated particles were visible in the lumen of the gut, but no uptake through the gut or the skin was observed.