For a mini-review published in the journal Particle and Fibre Technology in 2021, scientists wanted to evaluate whether Ti02 particles contributed to the development and/or exacerbation of irritable bowel disease, and whether they altered the four elements of intestinal barrier function: the intestinal microbiota, the immune system, the mucus layer, and the epithelium. The breakdown of these four elements can contribute to autoimmune, neurological, inflammatory, infectious, and metabolic diseases. Following their review, the researchers concluded: “Data indicate that TiO2 is able to alter the four compartments of IBF and to induce a low-grade intestinal inflammation associated or not with pre-neoplastic lesions.” 

But this is just the tip of the ice berg so many articles & studies are coming out challenging the safety of Titanium Dioxide in our food supply & personal care products.

In a lawsuit filed last week, a consumer alleged that Skittles were unfit for human consumption because the rainbow candy contained a known toxin – an artificial color additive called titanium dioxide.

SURFACES, CHEMISTRY & APPLICATIONS

There is some evidence that ingested titanium dioxide does not completely exit the body. A 2015 review of animal studies and a few human studies suggests titanium dioxide can get absorbed into the bloodstream and expose other organs to damage.

Cosmetics

In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

≥30.0

Lithopone B301, Lithopone B311 powder, brilliant white pigment used in paints, inks, leather, paper, linoleum, and face powder. It was developed in the 1870s as a substitute or supplement for lead carbonate (white lead), to overcome its drawbacks of toxicity, poor weathering, and darkening in atmospheres that contain sulfur compounds. Lithopone B301, Lithopone B311 powder is an insoluble mixture of barium sulfate and zinc sulfide that precipitates upon mixing solutions of barium sulfide and zinc sulfate. The precipitate is recovered by filtration, then calcined (roasted) at temperatures above 600° C (1,112° F). Although Lithopone B301, Lithopone B311 powder has been replaced in many applications by titanium dioxide, it is still widely used in a number of products, such as water paints.

When looking for suppliers of r 996 titanium dioxide, it is important to consider a few key factors. First and foremost, the quality of the product is paramount. r 996 titanium dioxide suppliers are known for their high-quality products that meet industry standards and specifications. This ensures that the end products manufactured using this pigment are of top-notch quality.

Another challenge facing TiO2 industry suppliers is the increasing environmental regulations and sustainability requirements. The production of TiO2 can have environmental impacts, such as energy consumption and waste generation. Suppliers must invest in sustainable practices and technologies to minimize their environmental footprint and meet regulatory requirements.

White crystalline powder. It is a mixture of zinc sulfide and barium sulfate. The more zinc sulfide it contains, the stronger the hiding power and the higher the quality. Density 4.136～4.34 g/cm3, insoluble in water. It easily decomposes when exposed to acid to produce hydrogen sulfide gas, but does not work when exposed to hydrogen sulfide and alkaline solutions. It turns into light gray after being exposed to ultraviolet rays in the sun for 6 to 7 hours, but it still returns to its original color when placed in a dark place. It is easy to oxidize in the air and will agglomerate and deteriorate when exposed to moisture.