Lithopone is an inorganic white pigment, obtained from co-precipitation of Zinc sulfide (ZnS) and Barium sulfate (BaSO4). Titanium Dioxide (TiO2) has replaced Lithopone as a white pigment in majority applications as TiO2 is more durable. However, it is much cheaper than TiO2 and has advantages such as low binder requirement and good dispensability. As a white pigment, it can improve the substrate's weather resistance, and improve the fungicidal properties of paint formulations. Some of the major applications of Lithopone include manufacturing of paint pigments, plastic & rubber products, paper, printing inks, cosmetics, and leather & linoleum products. It is commercially available under names such as pigment white 5, Barium zinc sulfate sulfide, Becton White, C.I. 77115, Charlton White, Enamel White, and Zincolith. On the basis of content of ZnS, Lithopone is available at 28%-30% Lithopone and 60% Lithopone.

Among the raw materials for coating production, titanium dioxide is more ideal, followed by lithopone. The covering power of lithopone is only that of titanium dioxide, and the price of lithopone is much lower than that of titanium dioxide, so lithopone still occupies a large market share.

In conclusion, calcium carbonate and titanium dioxide are important minerals that are used in various industries. While they are both produced by manufacturers, they have different manufacturing processes and applications. Understanding the differences between these two minerals can help industries make informed decisions about which one to use for their specific needs.

Both P25TiO₂NPs (with or without vitamin B2) were not found beyond the epidermis in 99% of the analyzed TEM images (Fig. 8). This is coherent with previous findings showing that nanoparticles greater than 50 nm can not penetrate the skin, even in vivo models with movement, stretching, and friction [54]. However, in one of the zones, a few nanoparticles were observed inside a hair follicle. This could be due to the follicle exposure after the localized rupture of this physical barrier when rats were shaved in order to clean the area for cream topical administration. This finding suggests that nanoparticle-based sunscreen should not be applied on recently shaved or harmed skin, in order to avoid nanoparticle skin penetration.

However, the market could not sustain these high prices and strived for equilibrium, causing the prices to fall. Further, after the complete removal of restrictions, the factories churned out products at a much faster pace than the market offtakes. Hence, the manufacturers reduced their quotations to maintain positive product movement in the market. The spot prices of titanium dioxide averaged around 2264 USD/MT in June’23 in the Chinese market.

It is recommended to store Titanium Dioxide in a well-maintained and dry environment, safeguarding it from exposure to elevated temperatures, open flames, or aromatic chemicals. When transporting Titanium Dioxide pigments, they are commonly packaged in paper bags weighing 25 kg (50 lb) or in large bags constructed from woven polypropylene materials.

On absorption of UV light, photo-generated titanium dioxide particles create singlet oxygen, superoxide anions (O2-) and hydroxyl radicals (OH-) that are potent free radicals (1,2). Irradiated particles of titanium dioxide can induce oxidative damage to DNA (2) which can lead to the development of mutant cells and skin cancers (3,4,5,6) and lipid peroxidation of essential functions on the cell membrane (7).