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- The chemical industry is vast and diverse, encompassing everything from pharmaceuticals and cosmetics to paints and industrial chemicals. These products are manufactured by companies large and small, each contributing to the complex supply chain that keeps our world running smoothly.
While the FDA maintains that the regulated use of titanium dioxide is safe, the European Food Safety Authority and some other experts warn of potential, serious health risks.
Research has shown that, when ingested as a food additive, titanium dioxide and its nanoparticles can impact, alter, and/or damage important protective bacteria in the gut, along with the metabolic pathways of gut bacteria.
In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”
2C+O2→2CO2




Lithopone has therefore traditionally been used in stoppers and putties, jointing compounds and sealing compounds, primers and undercoats and in road-marking paints.
From dyes to flavorings, many people are becoming increasingly aware of the ingredients in their food.
ZnSO4 – BaS ➔ BaSO4*ZnS
High Scattering Power TiO2 DongFang R5566
Because of health risks, France banned titanium dioxide as a food additive in 2020. Two years later the European Union also banned titanium dioxide as a food additive.
Historically, the first mentions of zinc sulfide being utilized as a pigment were approximately sixty years before the everyday use of lithopone. Originally, it was thought to be appropriate for coloring rubber. In England, a patent was granted for this process. Two decades after this, the focus shifted to zinc sulfide as a suitable pigment for paint. The year 1874 witnessed the patenting of a manufacturing process for a novel white pigment composed of zinc sulfide and barium sulfate. Dubbed Charlton white or Orr’s white enamel, this began a new era for white pigments.
In its 2016 opinion, the ANS Panel recommended new studies be carried out to fill the gaps on possible effects on the reproductive system, which could enable them to set an Acceptable Daily Intake (ADI ). Uncertainty around the characterisation of the material used as the food additive (E 171) was also highlighted, in particular with respect to particle size and particle size distribution of titanium dioxide used as E 171.
Technical Specifications:(Standard:Q/SNBJ1-2012)
Titanium Dioxide Price Trends for the First Half of 2023
