Key Applications

Health advocates urge US regulators to ban common food coloring additive, by Tom Perkins, The Guardian, June 2, 2023

Titanium dioxide as used in sunscreens is commonly modified with other ingredients to ensure efficacy and stability. Examples of what are known as surface modifier ingredients used for titanium dioxide include stearic acid, isostearic acid, polyhydroxystearic acid, and dimethicone/methicone copolymer.

CSPI says it might reconsider its rating if specifications for food-grade titanium dioxide in the U.S. are updated to ensure nanoparticles are minimized, and new studies are conducted to assess its capacity to cause cancer or other health problems. 

In conclusion, the MBR9668 rutile titanium dioxide coating is a revolutionary product that enhances the quality, efficiency, and sustainability of coatings across various industries. As a leading supplier of this material, companies can provide clients with high-performance solutions that meet modern demands for durability and aesthetics. With its unique benefits and applications, MBR9668 stands out as a key component in the future of quality coatings, setting new standards in product performance and longevity.

In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

The Evolution and Impact of Anatase Titanium Dioxide Manufacturers

A  2023 study published in the journal Environmental Research, scientists examined the effect of titanium dioxide nanoparticles on important gut bacteria in mice. Their results showed “the growth inhibitory effects could be associated with cell membrane damage caused by titanium dioxide nanoparticles to the bacterial strains. Metabolomics analysis showed that TiO2 NPs caused alterations in multiple metabolic pathways of gut bacteria, such as tryptophan and arginine metabolism, which were demonstrated to play crucial roles in regulating gut and host health.” The researchers also found that four different neuroprotective metabolites “were significantly reduced” in urine and in vitro bacteria and vivo urine samples. The researchers concluded: “Increasing evidence implies that the gut microbiome plays a profound role in regulating host metabolism. Our results illustrated that TiO2 NPs hindered the growth of four beneficial gut bacterial strains.”

Due to its low binder requirement, lithopone provides paints with good flow and application properties. In the plastic processing industry, it is added to plastics to increase the plastic product’s UV tolerance, thus increasing its outdoor life. In the leather industry, it is one of the sulfide-based white pigments. It is also used in the production of linoleum floorings.