According to the American Chemistry Council, titanium dioxide (TiO2) is an inorganic substance that's used as a white powder in a variety of industrial and consumer goods, including in sunscreen, cosmetics, toothpaste, paint, plastics, food and more.

What is an exposure route? 

② Plastics: At present, it is the second largest user of titanium dioxide pigments, accounting for about 20% of the total demand for titanium dioxide. The amount of titanium dioxide used in plastic products will vary with the use requirements, generally between 0.5% and 5%. According to data from the National Bureau of Statistics, the production of plastic products in China increased from 57.81 million tons in 2012 to 81.84 million tons in 2019, with a compound annual growth rate of 5.1%. The amount of titanium dioxide increases accordingly.

The concern from animal studies is that high amounts of titanium dioxide have increased inflammation and colon tumor formation, said Dr. Johnson-Arbor. A 2021 review, meanwhile, suggested that using titanium dioxide as a food additive weakens the gut lining and worsens the progression of inflammatory bowel disease.

FAQ
Q1. Can I have a sample order for Titanum Dioxide?
A: Yes, We can express you 500 grams of samples, free of charge. And the quality is subject to the sample.

Q2. What about the lead time?
A: Within 15days after receiving the payment

Q3. Do you have any MOQ limit for Titanium Dioxidde?
A: 5MT

Q4. Is it OK to print my logo on the Titanium Dioxide Packing bag?
A: Yes. Please inform us formally before our production and confirm the design LOGO firstly.

Q5: What's the payment term?
A: T/T or L/C at sight

Duan et al. administered 125 mg/kg BW or 250 mg/kg BW of anatase TiO₂ (5 nm) intragastrically to mice continuously for 30 days. The exposed mice lost body weight, whereas the relative liver, kidney, spleen and thymus weights increased. Particles seriously affected the haemostasis of the blood and the immune system. The decrease in the immune response could be the result of damage to the spleen, which is the largest immune organ in animals and plays an important role in the immune response. Powel et al. demonstrated that TiO₂ NPs may trigger immune reactions of the intestine after oral intake. They showed that TiO₂ NPs conjugated with bacterial lipopolysaccharide, but not TiO₂ NPs or lipopolysaccharide alone, trigger the immune response in human peripheral blood mononuclear cells and in isolated intestinal tissue. This indicates that TiO₂ NPs may be important mediators in overcoming normal gut-cell hyporesponsiveness to endogenous luminal molecules, which may be particularly relevant to patients with inflammatory bowel disease, which is characterized by an abnormal intestinal permeability.