Titanium dioxide (TiO2) is used in a variety of personal care products, including sunscreens, pressed powders, and loose powders, as a UV filter or whitening agent. In lotions and creams (dermal exposure), it is not a risk for adverse health effects. However, when titanium dioxide is inhalable—as it may be when in powder form—it is considered a possible carcinogen by the International Agency for Research on Cancer.Titanium dioxide nanoparticles do not appear to confer any unique health hazards.
- In the world of industrial manufacturing, coating raw material manufacturers hold a crucial position. They are the backbone of an array of industries, from construction and automotive to electronics and aerospace, where coatings play a vital role in performance, aesthetics, and durability.
- TIO2, commonly known as titanium dioxide, is more than just a simple oxide of titanium. It possesses unique properties that make it an indispensable component in various industrial processes. Its high refractive index, strong ultraviolet absorption, and excellent chemical stability are just a few of the characteristics that contribute to its wide-ranging utility.
- Titanium Dioxide Industry Manufacturer A Comprehensive Guide
North America
According to the EFSA's Expert Panel on Food Additives and Flavorings 2021 opinion regarding titanium dioxide, it could not rule out a concern for genotoxicity from ingestion of the material based on a perceived gap in data on this risk, which serves as the basis for current ban, said a March report on the decision.
Earlier this year, a bill was introduced in the California legislature to ban the manufacture, sale and distribution of foods in the state containing titanium dioxide, along with four other harmful food chemicals.


Assessment of biocompatibility in prokaryotic cells
Tio2 Powder CR-930 Titanium Dioxide Free Sample
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Titanium dioxide manufacturer: Panzhihua Dongfang
Inflammation of the intestines
The refractive index of binders used in coatings and inks is around 1.55. Titanium Dioxide is preferably used as a scattering source because the pigment does not absorb visible light and it has a high refractive index.
Lithopone is rather nontoxic, due to the insolubility of its components. It has been used in medicine as a radiocontrast agent. Lithopone is allowed to be in contact with foodstuffs in the US and Europe.[1]

In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.”
Dongfang Titanium Industry R-5568 titanium dioxide with zinc salt stabilizer, zirconium, aluminum, silicon coating. It has the characteristics of high blue phase, easy dispersion, high weather resistance, high hiding power, low oil absorption, good system compatibility, and excellent processing rheology. It is a high-quality titanium dioxide for plastics. Dongfang Titanium R-5568 titanium dioxide is recommended to be widely used in polyolefin, PVC, ABS, PS and other color masterbatches, profiles, plates and pipes, and can also be used in leather color paste, oily paint and other industries.