The European Commission banned titanium dioxide as a food additive in the EU in 2022 after the European Food Safety Authority (EFSA) conducted an updated safety assessment of E171 and concluded the panel could not eliminate concerns about its genotoxicity.
- Overall, calcium carbonate and titanium dioxide are essential minerals in the global industrial market, with China playing a key role in their production and export. As demand for these minerals continues to grow, it will be important for China to invest in sustainable production practices and improve the efficiency of its mining and processing operations to meet global demand in a responsible manner.
- Titanium dioxide, a naturally occurring compound, is widely used in various industries due to its unique properties. This versatile white pigment is known for its excellent whiteness, opacity, and chemical stability. In this article, we will discuss the benefits of wholesale titanium dioxide and explore its applications in different sectors.
- Wholesale TI02 powder plays a critical role in photocatalysis, a process that harnesses sunlight to drive chemical reactions
- faible abrasivité grâce à une dureté faible
Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation.
Titanium Dioxide Raw Material Tio2 Powder
Basic Information:
- Calcium carbonate is a versatile mineral that is used in a variety of industries, including paper, paints, plastics, and pharmaceuticals. It is most commonly used as a filler and pigment in products such as paper, paints, plastics, and rubber. In the paper industry, calcium carbonate is used as a filler to increase the brightness and opacity of paper, while in the paint industry, it is used as a pigment to provide color and durability.
In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2. With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”
Physical and Chemical Properties
Analyst Insight
The cytotoxic effect was tested through the colorimetric assay employing 3′-[1-[(phenylamino) -carbonyl]−3,4-tetrazolium]-bis(4‑methoxy-6-nitro) benzene-sulfonic acid hydrate (XTT) by reading the absorbance at 490 nm after 3 h of incubation post treatment [28]. The absorbance is proportional to the metabolic rate of viable (live) cells.
What titanium dioxide is really emblematic of ... is the failure of FDA to look back at these old decisions and ask whether its decisions that were made in this case ... 56 years ago (in the 1966 approval) still hold up, he said.


Alterations in gut microbiota
High Scattering Power TiO2 DongFang R5566
Application:
1. Due to its rheological and optical properties, Lithopone offers technical and economic advantages wherever organic and inorganic resin systems need to be relatively highly pigmented for specific applications. Lithopone has therefore traditionally been used in putties, mastics, jointing and sealing compounds, primers, undercoats and marking paints. In powder coatings it is possible to replace TiO2 partially, very economically.
2. The low Mohs' hardness of Lithopone leads to low abrasiveness in comparison with TiO2.
3. Lithopone 30 % (= 30% zinc sulfide share) is proven to be of particular use as a TiO2 Substitute in thermoplastic masterbatches. Even at very high pigment loadings it disperses easily. A masterbatch containing 50 % TiO2 and 25 % Lithopone 30 % DS has the same hiding power as one containing 60 %TiO2. Cost savings are strongly related to the price ratio of Lithopone and TiO2 and the price of for example polyethylene or polypropylene.
4. The Lithopone batch has a much higher extrusion rate too. Furthermore the impact strength of many thermoplastics such as PP and ABS can be noticeably improved by using Lithopone as a TiO2 substitute. Generally spoken, Lithopone can be used at loadings up to 80 % by weight without causing polymer breakdown
In conclusion, titanium dioxide is a game changer for the coatings industry. With its excellent hiding power, UV resistance, durability and environmental friendliness, it adds significant value to paint formulations. Whether you're looking to renovate your walls or looking for a solid paint option for your exterior surfaces, titanium dioxide-infused paints are the answer. Embrace the brilliance and durability that titanium dioxide has to offer and enjoy the long-lasting and vibrant finish it brings to your living spaces.
14 Max
Based on this opinion, the European Commission and the Member States agreed to remove all uses of titanium dioxide as an additive in food. In January 2022, a Regulation withdrawing the authorisation to use titanium dioxide as a food additive in food products was adopted i.e. Commission Regulation (EU) 2022/63.
Wholesale Dio2 Cas 13463-67-7
The factory's commitment to quality is evident in its production process, which adheres to strict standards and regulations. By using advanced technology and techniques, CAS 13463-67-7 is able to produce titanium dioxide that meets the exact specifications of its customers. This ensures that the final product is of the highest quality and consistency, leading to better performance and results for the end-users.
In 2017, French researchers from the Institut National de la Recherche Agronomique (INRAE) were among the first to examine the effects of E171 nanoparticles on the body. They fed rats a dose of 10mg of E171 per kilogram of body weight per day, which was similar to human exposure in food. The research, which was published in Scientific Reports, showed that E171 was able to traverse the intestinal barrier, pass into the bloodstream, and reach other areas of the body in rats. Researchers also found a link between immune system disorders and the absorption of titanium dioxide nanoparticles.