- In the pharmaceutical sector, HPMC serves as an excipient in tablet coatings and as a binder in capsule and tablet formulations. Its mucoadhesive properties allow for controlled drug release, ensuring a consistent therapeutic effect. Additionally, it is used in ophthalmic solutions due to its non-irritating nature and ability to form a gel in the eye.
- Overall, the viscosity of HPMC grades plays a crucial role in determining their performance in different applications. It is important to select the right HPMC grade with the appropriate viscosity for each specific use case to achieve the desired results. By understanding the relationship between HPMC grades and viscosity, manufacturers can optimize their formulations and improve the quality of their products.
- Mechanism of Action
- One of the most significant advantages of HEC is its ability to form films and coatings. When HEC is dissolved in water, it forms a clear, colorless solution that can be applied to various substrates such as paper, metal, and plastic. The films formed by HEC are strong, flexible, and resistant to water, oil, and chemicals. This makes it an excellent choice for packaging materials, adhesives, and coatings for medical devices.
- form a protective barrier around the tablet, preventing moisture and oxygen
Function

Hydroxypropyl methyl cellulose (HPMC) is a cellulose derivative that was first developed and used in industrial and food applications starting in the 20th century. Its exact origin in terms of discovery and initial development is difficult to attribute to a single individual or organization, as research and development of cellulose derivatives has involved many scientists and companies at different times.
HPMC is produced through a chemical process known as etherification, in which natural cellulose is treated with hydroxypropyl chloride and sodium methoxide. This process alters the chemical structure of cellulose, making it water-soluble and giving it desired properties as a thickener, stabilizer and film-forming agent.
Production and Use over Time:
The use of HPMC in industrial and food applications has grown significantly since the mid-20th century, when researchers began to more fully explore the potential uses of cellulose derivatives. Its ability to act as a thickener, emulsifier and stabilizer has increased its adoption in a variety of industries, including pharmaceuticals, cosmetics and food.

The end product is vegan … but is it still natural? By contrast, gelatine has been the safe and trusted ingredient of choice for more than 100 years. And, as gelatine is a foodstuff, rather than a food additive, its use is neither limited nor restricted. It doesn’t even have an e-number. Furthermore, gelatin is GMO-free and sustainable, obtained from natural resources such as pig or bovine skin (by-products from the meat industry) using gentle hot water extraction. And, although being sourced from animals, specific varieties of gelatine can be used to meet the strict religious requirements of Hindus and Muslims, for example; even Kosher versions can be supplied.
HPMC
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
Self-leveling compounds:
(2)Physical property: